Respiratory system – Communicable Diseases Research

Utility of NO and H2S donating platforms in managing COVID-19: Rationale and promise

Review article

Published on 2022-11-012022-10-05
Journal: Nitric oxide : biology and chemistry
[Category] SARS, 바이오마커, 변종, 치료제,

COVID-19 and Gut Injury

Article

Published on 2022-10-202022-11-15
Journal: Nutrients
[Category] COVID19(2023년), SARS, 진단,

Increased respiratory dead space could associate with coagulation activation and poor outcomes in COVID-19 ARDS

Research article

Published on 2022-10-012022-10-05
Journal: Journal of critical care
[Category] 바이오마커,

Negative correlation between ACE2 gene expression levels and loss of taste in a cohort of COVID-19 hospitalized patients: New clues to long-term cognitive disorders

Article

Published on 2022-09-292022-11-16
Journal: Frontiers in Cellular and Infection Microbiology
[Category] SARS, 유전자 메커니즘,

[키워드] ACE1 ACE2 ACE2 expression ACE2 gene addition Ageusia Alu Analysis Angiotensin-converting enzyme Anosmia association Brain Cell cells cognitive Cognitive dysfunction Cohort consequence correlation COVID-19 disorder Effect evaluated expression expression level Factors gene expression level Genetic genetic association Health Hospitalized hospitalized patients human cell initial symptoms long-COVID long-COVID syndrome Loss of Smell loss of taste molecular nasopharyngeal negative New obligatory occur Olfactory epithelium outcomes penetration polymorphism prevalent priming protease Quantitative quantitative trait receptor Regression model Research Respiratory system RT-qPCR SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe COVID-19. Spread Symptom Symptoms tissue TMPRSS2 variable virus
[DOI] 10.3389/fcimb.2022.905757 PMC 바로가기

Singularity and Commonality in Response to SARS-CoV-2 in Lung and Colon Cell Models

Article

Published on 2022-09-092022-11-15
Journal: International Journal of Molecular Sciences
[Category] SARS, 치료제,

[키워드] addressed Analysis Antiviral APOBEC APOBEC3G APOBECs approach both virus Caco-2 Caco-2 cell Caco-2 cells Calu-3 Calu-3 cell Calu-3 cell line Cell cell line cellular cellular response Colon commonality Course COVID-19 dataset determine differentially expressed gene disease Diseases epithelial cell events Evidence expressed genes expression pattern Factors feature gastrointestinal tract gene expression level gene signatures host response intrinsic liver lung lung; manifestation Model molecular outcome Pathomechanism Pathways performed Perturbation provide question Research Respiratory system response SARS-CoV SARS-CoV-2 similarity Systems biology systems biology. the interferon tissue expression transcriptomic translational unique
[DOI] 10.3390/ijms231810451 PMC 바로가기

Aseptic osteonecrosis of the maxilla after severe COVID-19 infection and its treatment

Case report

Published on 2022-09-012022-10-05
Journal: Radiology Case Reports
[Category] 진단, 치료법,

Hydroxypropyl-beta-cyclodextrin (HP-BCD) inhibits SARS-CoV-2 replication and virus-induced inflammatory cytokines

하이드록시프로필-베타-사이클로덱스트린(HP-BCD)은 SARS-CoV-2 복제 및 바이러스 유발 염증성 사이토카인을 억제합니다

Article

Published on 2022-09-012022-09-11
Journal: Antiviral Research
[Category] COVID19(2023년), SARS, 변종, 신약개발,

[키워드] accompanied ACE2 Affect affected Alter antiviral activity Beta Beta-cyclodextrin Calu Calu-3 Cell cell line cell lines cholesterol COVID-19 COVID-19 disease cyclodextrin Cytokines cytopathic effects demonstrated disease drug Drug repurposing evidenced excipient experimental models expression Human Hyperinflammatory syndrome immunomodulatory effect in vitro in vivo Inflammation Inflammatory cytokine Inflammatory response inhibit inhibited inhibiting investigated microbial products mitigate Monocytes Particles pathophysiology primary human cells Proinflammatory cytokine proinflammatory cytokines protein levels reducing reduction in Replication replication complexes required Respiratory system safety profile SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV2 selected selective significantly systemic manifestations the disease therapeutic therapeutic agent therapeutic strategy These data treating Treatment viral cytopathic effect virus virus virus replication Virus replication. virus RNA
[DOI] 10.1016/j.antiviral.2022.105373 PMC 바로가기 [Article Type] Article

SARS-CoV-2 and Skin: New Insights and Perspectives

Article

Published on 2022-08-312022-11-15
Journal: Biomolecules
[Category] SARS, 유전자 메커니즘, 진단,

Database and AI Diagnostic Tools Improve Understanding of Lung Damage, Correlation of Pulmonary Disease and Brain Damage in COVID-19

데이터베이스 및 AI 진단 도구는 COVID-19의 폐 손상, 폐 질환 및 뇌 손상의 상관 관계에 대한 이해를 향상시킵니다.

Review

Published on 2022-08-222022-09-11
Journal: Sensors (Basel, Switzerland)
[Category] SARS, 치료기술,

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

SARS-CoV-2에 의한 폐 감염은 심각한 COVID-19에서 염증성 표현형과 함께 노화를 유도합니다: 바이러스 돌연변이 유발 가능성

Article

Published on 2022-08-182022-09-11
Journal: The European Respiratory Journal
[Category] Fulltext, SARS, 진단, 치료기술,

[키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus alveolar analysed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 APOBEC Apolipoprotein B AT2 Cell cells cellular senescence chronic inflammation Comorbidity Control coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CXCL8 cytokine Cytokines demonstrated disease DNA damage electron microscopy enzyme Enzymes epithelial exhibited expressed expression extrapulmonary sites H2Ax IL-1β IL-6 IL-6 expression immunocytochemistry immunohistochemistry implication in vitro induce infecting Infection Inflammation inflammatory phenotype Inflammatory response investigated kidney liver lung tissue sample marker Microscopy molecular mechanism multisystemic disease Mutagenesis Non-COVID-19 persistence phenotype progeny proinflammatory promote pulmonary respiratory Respiratory system SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 mutagenesis SARS-CoV-2 mutations SARS-CoV-2 strain SARS-CoV-2 strains SASP senescence senescent cell Sequencing analysis severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 Strains Vero-E6 cell Vero-E6 cells Viral mutagenesis
[DOI] 10.1183/13993003.02951-2021 PMC 바로가기 [Article Type] Article